Evaluation of Left Ventricle Performance in Patients with Ischemic Heart Disease Using Single Photon Emission Computed Tomography (SPECT) in Comparison with Echocardiography

  • Marrwa K. Mohammed Department of Physics, College of Science University of Baghdad, Baghdad, Iraq
  • Satar M. Kadam Surgery Department, College of Medicine, University of Baghdad, Baghdad, Iraq
  • Samar I. Essa Department of Physics, College of Science University of Baghdad, Baghdad, Iraq
Keywords: Ischemia severity, SPECT, echocardiography, left ventricular function and volumes

Abstract

Background: Ischemic heart disease is a major cause of the diastolic heart failure. Risk of heart failures was increased with microvascular coronary disease, which is characterized by left ventricular stiffness  with impaired relaxation and reduced compliance. Aim of this study is to estimate the effect of the severity of myocardium ischemia on the left ventricle ejection fraction and left ventricular volume using SPECT with 99mTc MIBI and to compare the results  with the echocardiography. The study included 117 subjects with ischemic heart disease were examined using SPECT and echocardiography techniques. The following parameters were measured: left ventricular end systolic volume (LVESV) , left ventricular end diastolic volume (LVEDV) , and left ventricular ejection fraction (LVEF). Results show that the change difference in EDV between the two technique was (98.79%) with insignificant (p > 0.05). While the change in the LVEF% between both groups was (105.40%) with significant (p <0.05). On the other hand, the difference in ESV and EDV/ESV ratio for both groups were (95.52%), and (103.61%) respectively with insignificant (p >0.05). It was concluded that SPECT with 99mTc MIBI had a good relation with the echocardiography technique for evaluation of the left ventricular ejection fraction and the left ventricular volumes. The results showed that  LVEF was decreased in patients with severe ischemic disease.

Published
2021-11-30
How to Cite
Mohammed , M. K., Kadam, S. M., & Essa, S. I. (2021). Evaluation of Left Ventricle Performance in Patients with Ischemic Heart Disease Using Single Photon Emission Computed Tomography (SPECT) in Comparison with Echocardiography. Iraqi Journal of Science, 62(11), 3871-3876. https://doi.org/10.24996/ijs.2021.62.11.8
Section
Physics