Blending a New Polymers Containing Oxadiazole Ring with PVA: Synthesis , Thermal Analysis and Biological Activity

Ruwaidah S.  Saeed; Thaer Saleh  Ghali; Zahraa A. Alwitry; Jumbad H. Tomma; Muna S.  Al-rawi

doi:10.24996/ijs.2025.66.12.1

Authors

Ruwaidah S. Saeed Department of Chemistry, College of Education for Pure Sciences, Ibn -Al-Haitham, University of Baghdad, Baghdad, Iraq https://orcid.org/0000-0002-8900-1557
Thaer Saleh Ghali Directorate of Education Dhi Qar, Ministry of Education , Dhi Qar , Iraq
Zahraa A. Alwitry Department of Chemistry, College of Education for Pure Sciences, Ibn -Al-Haitham, University of Baghdad, Baghdad, Iraq.
Jumbad H. Tomma Department of Chemistry, College of Education for Pure Sciences, Ibn -Al-Haitham, University of Baghdad, Baghdad, Iraq.
Muna S. Al-rawi Department of Chemistry, College of Education for Pure Sciences, Ibn -Al-Haitham, University of Baghdad, Baghdad, Iraq

DOI:

https://doi.org/10.24996/ijs.2025.66.12.1

Keywords:

Polymer blends, biological activity, heterocyclic polymers, 1,3,4-oxadiazoles, thermal analysis

Abstract

This study focused on the synthesis of novel polymers incorporating the 1,3,4-oxadiazole ring. Four polymers were specifically prepared by blending polymers (6-9) with polyvinyl alcohol (PVA) in defined ratios, resulting in the formation of blended polymers (10-13). The synthesized polymers were characterized using Fourier Transform Infrared (FTIR) spectroscopy and proton nuclear magnetic resonance (¹H-NMR). The results showed that the structure aligned with the proposed synthetic polymers. Furthermore, the physical and thermal properties were studied using scanning electron microscopy (SEM), thermogravimetric analysis (TGA) and Differential Scanning Calorimetry (DSC). Additionally, the biological activity was examined against two strains of pathogenic bacteria, Gram-negative (E. Coli) and Gram-positive (S. aureus). The findings demonstrated greater activity than Amoxicillin as a standard antibiotic.