Anticancer Activity of Sunflower (Helianthus annuns L.) Seeds oil against cell lines

Authors

  • Rakad Al-Jumaily Department of. Biology, College of Science, University of Baghdad
  • Nawal Al-Shamma Department of. Chemistry, College of Education, University of Baghdad
  • Mohammed Al-Halbosiy Biology Research Centre, University of Al-Nahrin
  • Laith Al-Shamma Department of. Biology, College of Science, University of Baghdad

Keywords:

Sunflower oil, , Cytotxoic effects, , Anticancer activity

Abstract

This study investigated the role of sunflower (Helianthus annuns L.) seed extracts as a cytotoxic agent against two cell lines (RD and L20B) using different concentrations of sunflower seeds oil 1.3 , 2.6 , 5.2, 10.4 , 20.8, 41.6 , 83.2 and 166.4 μg / ml for different exposure time (24 ,48 and 72 hrs). The results revealed a clear cytotxoic activity of sunflower seeds oil on growth of RD cancer cell line, and the effect was concentration-dependent.
The signification inhibition (P<0.05) was obtained at a concentration of 83.5 and 166.4 μg / ml as compared to control. In addition, the growth of RD cell line was more sensitive to sunflower seeds oil in comparison with the growth of L20B transform cell line. In conclusion, the extract showed inhibitory effect on cancer cell line and it is promising to use as anticancer drug.

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Published

2024-01-26

Issue

Section

Biology

How to Cite

Anticancer Activity of Sunflower (Helianthus annuns L.) Seeds oil against cell lines. (2024). Iraqi Journal of Science, 54(4Appendix), 1003-1009. https://ijs.uobaghdad.edu.iq/index.php/eijs/article/view/12411

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