Seroprevalence of Toxoplasma gondii and Cytomegalovirus in Aborted Women in Baghdad-Iraq

Abstract

Aim of this study was to assess the seroprevalence of Toxoplasmosis and
Cytomegalovirus (CMV) infection among aborted women. This study was
performed on 282 aborted women and 50 normal pregnant women (control group)
collected from Al-Yarmouk Teaching Hospital and Fatima Al-Zahraa Hospital for
Obstetrics and Children during October 2013 until the end of February 2014.The
samples were tested with Latex Agglutination Test (LAT) and CMV Rapid Test
Cassette as a primary screening for T. gondii and CMV antibodies in the women
sera. The primary tests showed a percentage of positive antibodies of T. gondii in
aborted women and normal pregnant women 99(35.1%), 13(26%) respectively,
while for CMV, it was 101(95.3%), 36(72%) respectively for the same groups,. The
second test used was Enzyme Linked Immuno-Sorbent Assay (ELISA) for the
positive sera in (LAT) test of T. gondii antibodies and for the positive sera in
cassette test of CMV antibodies. In this test, the women sera were divided into four
groups: (IgG+ & IgM-), (IgG+ & IgM+), (IgG- & IgM+) and (IgG- & IgM-) for
both aborted and normal pregnant women, the results of T. gondii were: 73(73.7%),
2(2%), 2(2%) and 22(22.3%) respectively compared with the control group
13(100%) for the first group only, while the results of CMV were: 98(71.5%),
0(0%), 2(2%) and 1(1%) respectively compared with the control group 35(97.2%)
and 1(2.8%) for the first and second group respectively.