Heterocyclic Synthesis of Some New Isoxazolidine Derivatives via 1,3-Dipolar Cycloaddition of Nitrones to Styrene

Akram Noori Mohammed Qaddo; Amjed Ahmed Abed

doi:10.24996/ijs.2022.63.10.4

Authors

Akram Noori Mohammed Qaddo Department of Chemistry, Education College for Girls, University of Mosul, Iraq https://orcid.org/0000-0003-1833-575X
Amjed Ahmed Abed Environment Department, North Refineries Company, Ministry of Oil, Iraq

DOI:

https://doi.org/10.24996/ijs.2022.63.10.4

Keywords:

nitrones, reduction, condensation reaction, 1,3-dipolar cycloaddition reaction, novel isoxazolidine derivatives

Abstract

A number of nitrones have been synthesized in three different procedures, starting with N-phenyl hydroxylamine, followed by the condensation reaction with some selected aldehydes. Furthermore, these nitrones were employed in the preparation of a number of new isoxazolidines. Cycloaddition reaction of nitrones to styrene produced the desired products.