The Correlation Between Salmonella typhi Associated Gallstone Formation and Gallbladder Cancer

Authors

  • Sahira I.H. Al-Sanjary Department of Biology, College of sceince, University of Mosul, Mosul, Iraq
  • Amera Mahmood M. Al-Rawi Department of Biology, College of sceince, University of Mosul, Mosul, Iraq

DOI:

https://doi.org/10.24996/ijs.2022.63.8.8

Keywords:

S.typhi, Gallstone, Cancer, FliC-d, CdtB

Abstract

    The current research focused on the detection of Salmonella typhi and its relationship with the formation of gallstone and gall bladder cancer. Samples were collected from patients aged between 32-67 years (males and females) in Mosul city hospitals. The samples included 30gallbladder fresh tissues from patients suffering from gallstone and 20 formalinfixed-paraffin embedded (FFPE) gallbladder tissue from patients confirmed with gallbladder cancer. The results showed that 33% S. typhi isolates were diagnosed from the tissue samples using conventional methods, biochemical tests and Vitek2. All fresh tissues samples gave positive PCR results for the presence of FliC-d and CdtB genes and 46% positivity for S. typhi compared with conventional methods, 64% for females, 35% for males and 40 % positive in the gallbladder cancer of which 62% were females and 37%males.

Downloads

Download data is not yet available.

Downloads

Published

2022-08-31

How to Cite

Al-Sanjary, S. I. ., & Al-Rawi, A. M. M. . . (2022). The Correlation Between Salmonella typhi Associated Gallstone Formation and Gallbladder Cancer. Iraqi Journal of Science, 63(8), 3332–3339. https://doi.org/10.24996/ijs.2022.63.8.8

Issue

Section

Biology