Synthesis of Silver Nanoparticles Using L.Rosa Flowers Extracts: Thermodynamic and Kinetic Studies on the Inhibitoty Effects of Nanoparticles on Creatine Kinase Activity

  • Riyam Lateef Khalaf Department of Chemistry, College of Science, University of Baghdad, Al-Jadria, Baghdad, IRAQ
  • Elham Majeed Ahmed Department of Chemistry, College of Science, University of Baghdad, Al-Jadria, Baghdad, IRAQ
  • Thikra Hasan Mathkor Department of Chemistry, College of Science, University of Baghdad, Al-Jadria, Baghdad, IRAQ
  • Hadeel Y. AL-Zubaidi Department of Chemistry, College of Science, University of Baghdad, Al-Jadria, Baghdad, IRAQ
Keywords: Silver nanoparticles, L.Rosa extract, green synthesis, creatine kinase, antibacterial activity

Abstract

      The present work investigates the synthesis of silver nanoparticles (AgNPs) by a biological method using L.Rosa flower extract and silver nitrate as precursors. Optimum conditions of synthesis were studies, such as pH, temperature, concentration of extract, concentration of silver nitrate, and stability with time. Characterization of AgNPs was carried out using UV-visible Spectroscopy, Scanning Electron Microscopy, X-Ray Diffraction, Fourier Transform Infrared and Transmission Electron Microscopy. The biosynthesized AgNPs exhibited inhibitory effects on creatine kinase activity in the sera of patients with myocardial infarction, compared with control subjects. Thermodynamic and kinetic studies of creatine kinase were performed. Further studies on other biological activities were performed to exploit AgNPs full potential. In conclusions, the present study utilize a simple, cheap and environmentally green method to synthesize silver nanoparticles. This single step procedure is more suitable for large scale production as it is rapid and eliminates the elaborate processes employed in the other bio-based protocols (e.g. by using fungi and bacteria).  

Published
2021-08-31
How to Cite
Khalaf , R. L., Ahmed, E. M., Mathkor, T. H., & AL-Zubaidi, H. Y. (2021). Synthesis of Silver Nanoparticles Using L.Rosa Flowers Extracts: Thermodynamic and Kinetic Studies on the Inhibitoty Effects of Nanoparticles on Creatine Kinase Activity. Iraqi Journal of Science, 62(8), 2486-2500. https://doi.org/10.24996/ijs.2021.62.8.1
Section
Chemistry