The Effects of the Aqueous Extract of the Leaves of the Local Plant Eruca sativa on Lipid Profile and Some Minerals in the Blood of Male White Mice

  • Sardar Mohammed Weli Nursing Department, Research Center, Technical College of Health, Sulaimani-Polytechnic University, Sulaimani, Iraq https://orcid.org/0000-0002-4453-515X
  • Sattar Ibrahim Kareem Medical laboratory science, college of health science, University of human development. Medical Laboratory
  • Osama Hamid Shareef Technique Department, Research center, Halabja Technical Institute, Sulaimani Polytechnic University. Sulaimani, Iraq
  • Hwda Ghafoor Rauf Medical laboratory science, college of health science, University of human development.
  • Chro Ghafoor Raouf Medical laboratory science, college of health science, University of human development. Medical Laboratory Department, Research center, Technical College of Health, Sulaimani Polytechnic University. Sulaimani, Iraq
  • Abdullah Ahmed Hama Medical laboratory science, college of health science, University of human development. Medical Laboratory Department, Research center, Technical College of Health, Sulaimani Polytechnic University. Sulaimani, Iraq
Keywords: E. sativa, lipid profile, calcium, magnesium

Abstract

Eruca sativa, commonly known as rocket salad, is a popular vegetable to which a wide range of health benefits are attributed. This study aimed to examine the effects of the aqueous extract of E. sativa leaves on lipid profile and some minerals, such as calcium and magnesium, in blood of male albino mice under normal physiological condition. Two experiments were separately conducted, each with eighteen male albino mice divided into 3 equal groups, which included control, treated group (1), and treated group (2) which were orally administrated with 0, 0.2 and 0.4 mg/kg body weight, respectively, of the leaves extract for 28 days. In the first experiment, serum lipid profile, including cholesterol, triglyceride, HDL, LDL and VLDL, were estimated. In the second experiment, serum calcium and magnesium were estimated. The results showed that E. sativa have effects on lipid profile by decreasing cholesterol, triglyceride, and LDL levels, but increasing that of HDL. In addition, E. sativa increased the levels of both calcium and magnesium. This study concludes that E. sativa leaves exerts possibly beneficial effect on lipid profile and calcium and magnesium levels in albino male mice under normal conditions.

Published
2021-04-29
How to Cite
Weli, S. M., Kareem, S. I., Shareef, O. H., Rauf, H. G., Raouf, C. G., & Hama, A. A. (2021). The Effects of the Aqueous Extract of the Leaves of the Local Plant Eruca sativa on Lipid Profile and Some Minerals in the Blood of Male White Mice. Iraqi Journal of Science, 62(4), 1088-1093. https://doi.org/10.24996/ijs.2021.62.4.5
Section
Biology