The Relationship Between Infertility and Infection with Clarithromycin Resistant Strain of Helicobacter Pylori in Iraq

  • Shiamaa G. Abid Department of Biology, College of Science, Baghdad University, Baghdad, Iraq
  • Rana S. Aboud Department of Biology, College of Science, Baghdad University, Baghdad, Iraq
Keywords: male infertility, 23SRNA, H.pylori, Real time PCR, Clarithromycin

Abstract

The relationship between infertility and Helicobacter pylori infection was investigated; samples from thirty-five infertile patients (aged 20-49 years) were collected from Kamal Al-Samaraei hospital , Baghdad, Iraq during the period from the first of February until April 2018. These patients were compared with 10 apparently fertile individuals who served as a control. The study was carried out to detect the DNA of H.pylori in both serum and seminal fluid of male infertile patients and for the control group by Real-Time Polymerase Chain Reaction (RT-PCR) technique. The results revealed that there was a significant difference (P<0.01) in the detection of DNA of H.pylori between patients and control groups. thereby the percentage level of H.pylori DNA in serum was 80% and in the seminal fluid was 0 %. As a result, we strongly suggest that the infection with H. pylori plays an important role in male infertility.

Published
2020-08-28
How to Cite
Abid, S. G., & Aboud, R. S. (2020). The Relationship Between Infertility and Infection with Clarithromycin Resistant Strain of Helicobacter Pylori in Iraq. Iraqi Journal of Science, 61(8), 1874-1879. https://doi.org/10.24996/ijs.2020.61.8.3
Section
Biology