THE EFFECT OF glycyrrhiza glabra AND DIOSPYROS KAKIFRUITS IN INHIBITING THE CHROMOSOMALABERRATIONS RESULTED FROM SODIUM SULFATETREATMENT IN HUMAN LYMPHOCYTE

Abstract

To study the role of Glycyrrhiza glabra and Diospyros kaki fruits extracts, active
compounds were detected. The first extract contained glycoside, tannines, alkaloids,
saponines, terpines, steroides, flavones and coumarins, while the second extract
contained phenolics and resins in addition to the compounds mentioned above with
an exception of alkaloids and coumarins.
The inhibition effect of the extracts on the chromosomal aberration resulted from
sodium sulfate as mutagenic agent in human lymphocyte cells (In vitro) was evaluated at concentrations of 10, 15, 25, 50, 100 mcg/ml. Results showed
increasing in inhibition of the extracts on chromosomal aberration with the increase
of the concentrations used and its interaction.