EFFECT OF ANTIBIOTICS TREATMENT ON HUMORAL IMMUNITY IN SHEEP VACCINATED WITH B. melitensis REV.1 VACCINE

Authors

  • I. Aldabagh Nineveh veterinary hospital. Ninewa-Iraq.
  • M. Mohammad Nineveh veterinary hospital. Ninewa-Iraq.
  • M . Ali Nineveh veterinary hospital. Ninewa-Iraq.

DOI:

https://doi.org/10.24996/ijs.2011.52.1.%25g

Keywords:

ANTIBIOTICS , HUMORAL

Abstract

The aim of this study was to examine the effects of different antibiotics administered intramuscularly with a different administration times on the humoral immune response resulted from intraocular vaccination with attenuated B. melitensis Rev.1 vaccine in sheep. The results showed a significant difference in the effect of different antibiotics used with a significant difference according to the administration time between 0 time, 7 and 14 days from vaccination. Oxytetracycline and amoxicillin significantly inhibit the humoral immune response when administrated at 0, 7 and 14 days of Brucella vaccination comparing with groups treated with sulphadimidine, penicillin-dihydrostreptomycin and the non-vaccinated groups while sulphamethazine – trimethoprim inhibit the humoral immune response when administrated at 0 time of vaccination comparing with groups treated with sulphadimidine, penicillin-dihydrostreptomycin and the non-vaccinated groups. The results indicate that the failure of Brucella vaccination could happen when antibiotics administered within the first 14 days after vaccination.

Downloads

Download data is not yet available.

Additional Files

Published

2024-05-30

Issue

Section

Biology

How to Cite

EFFECT OF ANTIBIOTICS TREATMENT ON HUMORAL IMMUNITY IN SHEEP VACCINATED WITH B. melitensis REV.1 VACCINE. (2024). Iraqi Journal of Science, 52(1), 20-29. https://doi.org/10.24996/ijs.2011.52.1.%g

Similar Articles

1-10 of 101

You may also start an advanced similarity search for this article.