Assessment of Inflammation, Comorbidity and Demographic Factors in Patients with Kidney Disease in Baghdad

Abstract

     Inflammation markers are significantly higher among hemodialysis (HD) patients, which have been associated with chronic activation of the immune system. Hemodialysis centers in Baghdad appear to be taking measures with low adequacy and frequency of dialysis sessions, which can be a reason for decreased kidney functions. Therefore, the objective of this study focuses on the assessment of different aspects of hemodialysis for regular HD patients in Baghdad, including inflammatory markers (serum C-reactive protein, CRP, and erythrocyte sedimentation rate, ESR), dialysis dose, comorbidities, and demographic factors for a period of one year (2018), the assessment covered four major hospitals in Baghdad namely (Al-Kindi, Baghdad Educational, Al-Imamain Al-Jwadian, and Al-Yarmouk). The study involved 320 adult (chronic kidney disease; non hepatitis virus) patients (55% male and 45% female) treated with regular hemodialysis. When compared with the normal values ​​specified by manufacturers for the number of measurement of these indicators. Inflammation markers were high in HD patients were  66.2% of patients recorded elevated of CRP and 87.7% for ESR with no significant difference between males and females, but the origin of chronic inflammation in the patient's remains unclear. Moreover, the majority of HD patients were non-educated; illustring that higher education is possibly associated with lower disease incidence as compared to those who never finished high school. Finally, most of these hospitals, average hemodialysis treatment lasts about three hours and is done two times per week.