Anti Obesity and Lipid - Lowering Effect of Lactobacillus Spp. as Probiotic on the Obese Rat.

Abstract

The effects of Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus casi
and Lactobacillus rhomunas on the body weight and lipid metabolism on obese rats
were evaluated. In the body weight, the results showed significant deference
between rat groups, the group that consumed 3 probiotic strains showed reduction in
the body weight with ratio 16.63% while the group consumed 2 probiotic strains
showed decreasing with ratio 17.62% compared with control group which increased
in the body weight.In the effeci of probiotics on lipid metabolisim the results
showed significant deference between rat groups, the group that consumed 3
probiotic strains showed decreasing in the cholesterol with ratio 50.7%, triglyceride
with ratio 48.8 %, LDL with ratio 51% and elevated of HDL level with ratio 45%,
while the group consumed the 2 probiotic strains showed decreasing in the
cholesterol with ratio 48.3%, triglyceride with ratio 43.3 %, LDL with ratio 27.4%
and elevated HDL level with ratio 26%. The study suggests that LAB
supplementation has hypocholesterolemic and anti obesity effects in rats. These
strains might be able to improve the intestinal microbial balance and potentially
improve intestinal transit time.