The Role of Probiotics in Treating Echinococcosis in Mice

Arkan Saeed  Sheet; Abdulkhaliq Alwan  Mohiemeed; Asmaa Abdulaziz  Ali

doi:10.24996/ijs.2024.65.12.%g

Authors

Arkan Saeed Sheet Department of Biology, College of Education for Pure Sciences, Tikrit University, Tikrit, Iraq
Abdulkhaliq Alwan Mohiemeed Department of Biology, College of Science, Tikrit University, Tikrit, Iraq
Asmaa Abdulaziz Ali Department of Biology, College of Education for Pure Sciences, University of Mosul, Mosul, Iraq https://orcid.org/0000-0001-7284-6919

DOI:

https://doi.org/10.24996/ijs.2024.65.12.%25g

Keywords:

Lactobacillus plantarum, Bifidobacterium lactis, Streptococcus thermophiles, Echinococcosis

Abstract

This study investigated the role of probiotics in treating echinococcosis, considering three time periods (3, 5, and 7 months) and three bacterial dilutions. Mice were injected subperitoneally before and after primary infection with the rudiments. Before infection, the mice were injected with the Pro-30Max probiotics twice, with 48 hours interval. On the fifth day, they were infected with protoscoleces, and after 48 hours they were treated with the bacteria. The injections continued every 72 hours for all periods. A decrease in the number and weight of hydatid cysts was recorded reaching the value of 0.00 mg. Whereas a decrease in the weight of the liver and spleen and their inflation factors were recorded after 7, 5 and 3 months. The lowest weight of the liver and spleen reached 1.2869 and 0.196 grams, and their lowest inflation factors were 36.106 and 7.118, respectively, when treated with a dilution of 18 × 10⁸ compared with the control group. At the same dilution, the percentage reduction of hydatid cysts increased after 7 months, reaching 100% compared with the control group.