Study of the Association of Some Tumor Markers and Serum Protein Electrophoresis Patterns with Breast Cancer in Iraqi Population

Authors

  • Yassin B. Ridha Awachti Department of Medical laboratory Techniques, Dijlah University, Baghdad, Iraq
  • Dina Hamid Sahib Department of biotechnology, college of science, university of Baghdad, Baghdad, Iraq
  • Jwan.Y.B. Alfaily College of Veterinary Medicine, University of Baghdad, Baghdad, Iraq
  • Zahraa J. Mohammed Alkarama teaching hospital, Baghdad, Iraq

DOI:

https://doi.org/10.24996/ijs.2025.66.1.6

Keywords:

Breast cancer, Serum protein electrophoresis, Carcinoembryonic antigen, Carcinoma Antigen 15.3, Carcinoma antigen 125

Abstract

Breast cancer is the most commonly diagnosed cancer and a leading cause of cancer mortality among females worldwide. The recruitment of less invasive serum protein electrophoresis and serum breast cancer tumor markers as monitoring factors for patient response to therapy is still controversial.

 Hence, the present study aimed to designate serum protein electrophoresis pattern of carcinoembryonic antigen (CEA), carcinoma antigens (CA125  and CA 15-3) as novel biomarkers in monitoring breast cancer patients under and post radiotherapy or chemotherapy.

Samples included 23 breast cancer women patients after mastectomy and under or post chemotherapy and radiotherapy. Tumor markers CEA, CA 15-3, and CA 125 were measured by using electrochemiluminescence method used in Cobas ®. Total serum protein was performed by using commercially available kits suitable with semiautomated chemistry analyzer. Quantitative estimation of serum proteins was accomplished by agarose serum protein electrophoresis.

Downloads

Published

2025-01-30

Issue

Section

Biology

How to Cite

Study of the Association of Some Tumor Markers and Serum Protein Electrophoresis Patterns with Breast Cancer in Iraqi Population. (2025). Iraqi Journal of Science, 66(1), 66-76. https://doi.org/10.24996/ijs.2025.66.1.6

Similar Articles

1-10 of 1503

You may also start an advanced similarity search for this article.