Study the Effect of some Medical Plants in Biofilm Formation and Antibiotic Sensitivity for Klebsiella Pneumoniae

Abstract

Twenty clinical and fecal samples (ten clinical samples from patients attending to
Imam Ali Hospital and ten chicken faeces samples collected from local poultry farm
in Baghdad city) collected during December 2015, for isolated Klebsiella
pneumoniae. All K. pneumoniae isolates were extended-spectrum β- lactamase
producers and biofilm formation. The activities of two selected K. pneumoniae
isolates for their biofilm formation and susceptibility to antibiotics after treatment
with several plants extracts were investigated. The results of water and 60% ethanol
extracts for Matricaria chamomile flowers, Alhagi maurorum leafs, Syzygium
aromaticum buds (clove) and Arctium minus leafs were showed reduction of biofilm
formation and change the ability of antibiotic susceptibility for these two tested K.
pneumoniae isolates. The indirect effect of plants extracts on the bacterial growth
may be causing indirect effect on the metabolic activity and DNA (chromosome or
plasmid) of cells. All tested plant extract contain many antimicrobial and antioxidant
component by using GC-mass.