Study theeffect ofTamoxifenon Lipid profilein Male Albino Rats

Authors

  • Aqeel H. Qasim Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq.
  • Abed H. Baraj Department of Biology, College of Science, University of Baghdad, Baghdad, Iraq.

DOI:

https://doi.org/10.24996/ijs.2017.58.4A.5

Keywords:

Tamoxifen, Albino rats, lipid profile

Abstract

Tamoxifen(TAM) is an effective anticancer drug. This study was conducted to evaluate the side effects of Tamoxifenon the lipid profile. 40 rats divided into 4 equal groups,3 groups were given different doses (30, 40, 50)mg/kg body weight of TAM three times a week for 8 weeks as well as control group that was given with physiological solution.At the end ofexperiment, The results showed significant differences in the treated groups were the results showed a significant degrees (p<0.05) in the HDL level in the treatment group (50mg/kg) while the three groups showed a significant increase in the levels of (Ch, TG, LDL, VLDL). The results of the study showed that Tamoxifen caused an accumulation in fats.

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Published

2021-11-29

Issue

Section

Biology

How to Cite

Study theeffect ofTamoxifenon Lipid profilein Male Albino Rats. (2021). Iraqi Journal of Science, 58(4A), 1815-1819. https://doi.org/10.24996/ijs.2017.58.4A.5
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