The Efficiency of Apple Vinegar as A Solvent in Comparison to Water and Ethanol for The Extraction of Some Plants used Against Candida Spp. Biofilm Formation

  • Sinai W. Mohammed Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
  • Faheema Jabbar Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
  • Hanan J. Nayyef Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
  • Maysaa K. Al-Malkey Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
  • Khawla I. Misha'al Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
  • Estabraq Ab. taqi Tropical Biological Research Unit, College of Science, University of Baghdad, Baghdad-Iraq
Keywords: Antibiofilm activity, antifungal agents, C. albicans, apple vinegar

Abstract

Apple vinegar has many uses that include burn and wound healing and as an antimicrobial agent against different microorganisms, but not as a solvent. Therefore, this study aimed to use commercial apple vinegar as solvent to the plants of  roselle (Hibiscus sabdariffa), green tea (Camellia sinensis), and clove (Syzygium aromaticum). The effects of apple-vinegar extracts of these plants were compared with those of aqueous and ethanolic extracts against biofilm formation by Candida genus. Clove vinegar extract demonstrated antibiofilm activity against C. albicans, alone (2.4907± 0.382) or in combination with the antifungal agents fluconazole (1.689±0.33), nystatine (1.941±0.64), and clotrimazole (2.0353±0.71819). These plant extracts possessed a variable number of antimicrobial compounds, as tested by the HLPC technique. Therefore, apple vinegar was the most efficient solvent, in comparison with the other solvents used in this study, to obtain some phytochemical compounds from the tested plants that have antibiofilm activity against C. albicans.

Published
2021-07-01
How to Cite
Mohammed, S. W., Jabbar, F., Nayyef, H. J., Al-Malkey, M. K., Misha’al, K. I., & taqi, E. A. (2021). The Efficiency of Apple Vinegar as A Solvent in Comparison to Water and Ethanol for The Extraction of Some Plants used Against Candida Spp. Biofilm Formation. Iraqi Journal of Science, 62(6), 1829-1835. https://doi.org/10.24996/ijs.2021.62.6.8
Section
Biology