THE POSSIBLE ROLE OF MUMPS VIRUS INTHE DEVELOPMENT OF INSULIN DEPENDANTDIABETES MELLITUS

R.   Taha; Dawood   D.; Mustafa   K.

doi:10.24996/ijs.2010.51.4.%g

Authors

R. Taha College of Midicine , Nahrin University. Baghdad -Iraq.
Dawood D. College of Health and Medical Technology, Foundation of Technical Education, Baghdad -Iraq.
Mustafa K. Educational Laboratories, Baghdad. Baghdad -Iraq.

DOI:

https://doi.org/10.24996/ijs.2010.51.4.%25g

Keywords:

POSSIBLE, DEVELOPMENT

Abstract

Mumps is an acute viral illness associated with different types of complications,
Pancreatitis is one of infrequent mumps complications followed by diabets mellitus
type one in few cases. The present study was designed to determine whether a
relationshipe exposure to mumps by natural infection or vaccination with
MMRvaccine and diabetes type one.
Seventy two patients with Insulin dependent diabetes mellitus exposed to mumps by
vaccinor natural infection compared with ١٨ (healthy) age and sex matched control
were included in this study . Blood samples were taken for investigation of Glutamic
acid decarboxylasw antibody (GADA), Islet cell antibody (ICA) and Mumps IgG
Antibody by using ELISA and immunoflorescent technique.
Islet cell antibody was detected in ١٣ (١٨.١%) patients ٦ (٨.٣%) males and ٧ (٩.٧%)
females. GADA was detected in ٤٥ patients (٦٤.٥%) ٢٤ males (٣٣.٣%) and ٢١
(٢٩.٢%) females. Mumps IgG Antibody was found in ٢١ (٢٩.٢%) of patients